Cisplatin salt wasting

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August undefined, 2024

WebCisplatin Induced Renal Salt Wasting Syndrome: An Uncommon Diagnostic Distinction Session Information. Fluid, Electrolyte, and Acid-Base Disorders: Case Reports ... and recovery is the rule although recurrence is common. While carboplatin is less toxic, cisplatin has unequivocal superiority in most of the cancers in which it is used, making it ... WebFeb 1, 2016 · Cisplatin may produce renal salt wasting causing symptomatic orthostatic hypotension and hyponatremia associated with abnormalities of the renin-aldosterone …

Renal Salt-Wasting Syndrome in a Patient With Cisplatin-Indu

WebMar 1, 2024 · Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude of renal disorders including acute kidney injury with reduced glomerular filtration, Fanconi syndrome, and renal tubular acidosis, nephrogenic diabetes insipidus and renal salt wasting syndrome. WebOct 6, 2016 · In the clinical setting, the most common and important manifestation of cisplatin nephrotoxicity is AKI, which can be progressive and even irreversible. Other renal manifestations include hypomagnesaemia, salt wasting, a … iphone charger device may not be supported

Kidney Week - Abstract Details (2024) - American Society of …

WebBoth renal salt-wasting syndrome (RSWS) and syndrome of inappropriate antidiuretic hormone secretion (SIADH) have been reported as the underlying mechanisms for … WebCisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, … WebDifferential diagnosis of hyponatremia induced by cisplatin-containing chemotherapy: syndrome of inappropriate secretion of antidiuretic hormone (SIADH) or renal salt … orange blossom special 14 year old fiddler

Profound hyponatremia and dehydration: A case of …

WebJan 25, 2012 · Hyponatremia associated with syndrome of inappropriate secretion of antidiuretic hormone (SIADH) or renal salt-wasting syndrome (RSWS) after platinum-based chemotherapy is not uncommon. However, no reports of RSWS following taxane monotherapy have been previously published. WebRenal salt wasting syndrome has been described in 17 case reports since 1984. It is a rare side effect of cisplatin that manifests with polyuria, hypovolemia, and hyponatremia, and, because of similarities in clinical settings and laboratory values, it is frequently misdiagnosed as a syndrome of inappropriate antidiuretic hormone. orange blossom shower curtainWebRenal salt wasting: urine Na will be high. Causes include salt-wasting nephropathy, adrenal insufficiency, cisplatin, and thiazide diuretic use. Euvolemic: Hypothyroidism: check TSH. Glucocorticoid deficiency: check AM cortisol. orange blossom scented oil

"WebMay 19, 2024 · Rarely, cisplatin-related hyponatremia may result from Renal Salt Wasting Syndrome ( 33 ). Hypernatremia can also develop with cisplatin due to acquired nephrogenic diabetes insipidus with ensuing … " - Cisplatin salt wasting

Cisplatin salt wasting

Profound hyponatremia and dehydration: A case of cisplatin …

WebCisplatin-Induced Renal Salt Wasting Requiring over 12 Liters of 3% Saline Replacement Case Rep Nephrol. 2024;2024:8137078. doi: 10.1155/2024/8137078. Epub 2024 May 10. Authors Phuong-Chi Pham 1 , Pavani Reddy 1 , Shaker Qaqish 1 , Ashvin Kamath 1 , Johana Rodriguez 2 , David Bolos 2 , Martina Zalom 2 , Phuong-Thu Pham 3 …

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WebSep 1, 2002 · (6) The mechanism of cisplatin-induced hyponatremia is thought to be mainly renal salt wasting syndrome (RSWS), (7) (8) (9) (10) (11) (12) (13) and sometimes the syndrome of inappropriate... WebWe diagnosed this clinical condition as renal salt-wasting syndrome (RSWS) on the basis of dehydration and high urinary sodium excretion at the onset. In the second course of chemotherapy, CDDP was replaced with carboplatin (CBDCA); consequently, hyponatremia was not observed.

WebNov 1, 2003 · In 1988, Hutchison et al reported profound urinary sodium wasting in 7 of 70 patients treated with cisplatin over an 18- month period in 1 institution. 1 All the patients were men with carcinomas (including 1 patient with SCLC) and presented 2-4 months after starting cisplatin-based therapy with signs of vol- ume depletion, urinary salt wasting ... WebCisplatin is an intercalating agent that induces apoptosis of cancer cells, and it has been the most widely used drug in the first-line chemotherapy. However, the increase in cisplatin-resistant cancer cells has become a major obstacle in clinical management of cancers (Amable, 2016 ).

Web42%–100% of patients depending on total cisplatin dose and length of exposure. Hypomagnesemia and renal magnesium wasting may persist for up to 6 years after initial dose (5). Renal salt wasting syndrome has been reported in up to 10% of patients, manifesting as hyponatremia and severe ortho-static hypotension in the setting of high … WebFeb 16, 2024 · Cisplatin Carboplatin 11% (carboplatin likely lower) SIADH, renal salt wasting (tubular damage) Cyclophosphamide Ifosfamide 9%–52% SIADH BCR-ABL tyrosine kinase inhibitors Imatinib 9%–13% SIADH BRAF and VEGF tyrosine kinase inhibitors Axitinib Sorafenib Brivanib Pazopanib Sunitinib 16%–39% SIADH EGFR …

WebDec 10, 2024 · A 20-year-old man developed renal salt wasting syndrome (RSWS) during treatment with cisplatin for germ cell testicular cancer. The man had non-seminomatous …

WebCisplatin induces both inflammation and vascular injury, which further promotes kidney injury. In addition to AKI, cisplatin causes proximal tubulopathy, salt wasting, loss of urinary concentrating ability, and magnesium wasting. View chapter Purchase book T cells in kidney injury and regeneration Li Li, ... iphone charger extra longWebContact ASN. 1401 H St, NW, Ste 900, Washington, DC 20005. [email protected]. 202-640-4660 orange blossom scented soapWebFeb 1, 2016 · The marked urinary losses of sodium in combination with a negative sodium balance led to the diagnosis of cisplatin-induced renal salt wasting syndrome (RSWS). The subsequent clinical... orange blossom special clogging routineWebSIADH, renal salt-wasting syndrome, and salt loss caused by vomiting and/or anorexia, should be diagnosed as accurately as possible in future studies. ... Alhosaini MN, Patel A. Cisplatin-induced renal salt wasting syndrome. South Med J. 2010;103(8):793–799. 5. Raftopoulos H. Diagnosis and management of hyponatremia in cancer patients. orange blossom special clogging cue sheetWebCisplatin-induced renal salt wasting requiring over 12 liters of 3% saline replacement. Case Rep Nephrol 2024; 2024:8137078 Cadacio C, Pham PT, Bhasin R, Kamarzarian A, Pham PC. Multiple electrolyte and metabolic emergencies in a single patient. Case Rep Nephrol 2024:4521319 iphone charger for harley davidsonWebCisplatin is a potent antineoplastic agent derived from platinum and commonly used in the treatment of head ... both water restrictions and sodium supplementation may be appropriate when differentiating between diagnoses of renal salt wasting syndrome and syndrome of inappropriate antidiuretic hormone secretion. Fed Pract. 2024 December;38(12 ... orange blossom special chords fiddleWebCisplatin is known to induce Fanconi syndrome and renal salt wasting (RSW). RSW typically only requires transient normal saline (NS) support. We report a severe RSW case that required 12 liters of 3% saline. A 57-year-old woman with limited stage small cell cancer was admitted for cisplatin (80 mg/m 2) and etoposide (100 mg/m 2) therapy. orange blossom special drink