WebHemoglobin E – beta thalassemia: individuals who are doubly heterozygous for hemoglobin E and beta thalassemia have an anemia that can vary in severity, from mild ... Hemoglobin a1c. Hemoglobin A1c, also called A1c or glycosylated hemoglobin, is hemoglobin with glucose attached. The hemoglobin A1c test evaluates the average amount of glucose ... Web3 Mar 2024 · Alpha thalassemia is one of the hemoglobin variants that may falsely elevate or reduce HbA 1c measurement depending on the method and assay used due to analytical, biochemical, and biologic ...
Hemoglobin Abnormalities Affect A1c Testing for Diabetes
Web24 Aug 2024 · HbH disease, which is the most severe form of alpha thalassemia, causes hemolysis and a shortened RBC life span, which could produce a misleadingly low A1c result. 30 Alpha thalassemia is often co-inherited with HbS and HbE. Both conditions (variant and thalassemia) converge in causing an alteration of the glycation process. WebThe A1C test measures the amount of hemoglobin with attached glucose and reflects your average blood glucose levels over the past 3 months. The A1C test result is reported as a … tjs oak ridge
WHEN PAIRED HBA AND FASTING GLUCOSE DON’T MATCH, …
Web8 Mar 2024 · Does alpha thalassemia affect A1c? Results: In patients with two or three functional α-genes, HbA1c values were not significantly different from those of controls (P > 0.05); however, in individuals with α-thalassemia with one functional α-gene (i.e., HbH disease), HbA1c levels were significantly different from those of controls (P < 0.01). ... Web1 Apr 2001 · The frequency of thalassemia has been estimated to be ∼1 in 2350 in Japan ( 9) and even higher in North Africa ( 10 ). Hb E is the second most prevalent Hb variant worldwide and the third most prevalent variant in the US, after Hb S and C. Hb E is found primarily in Southeast Asia, especially among the Thai population ( 11 ). WebThe mean value of glycosylated hemoglobin A1C in non-diabetics i.e controls and β-thalassemia traits i.e cases was 5% and 5.04% (p-value>0.005) i.e mean level of glycosylated hemoglobin A1C were comparable in both cases and controls. Conclusion: Hemoglobin A1C can be used to monitor glycemic control in β-thalassemia traits. tj's oak ridge nj