WebSep 11, 2024 · ORR and PFS (or TTP) The reported correlation coefficients (Pearson’s r or Spearman’s r s) between absolute ORR and PFS ranged from −0.72 to 0.96, ... Web(1) Background: Cabozantinib is approved in sorafenib-exposed advanced hepatocellular carcinoma (aHCC). We evaluated the real-life pattern of use, efficacy, and tolerability of cabozantinib in aHCC. (2) Methods: This territory-wide study included consecutive aHCC patients who received cabozantinib between February 2024 and September 2024 in Hong …
A systematic review of meta-analyses assessing the validity of ... - Nature
WebApr 7, 2024 · Objective response rate (ORR) was defined as the proportion of patients achieving complete/partial response as best radiological response. ... The lack of statistical significance in multivariable analysis of TTP was likely due to the low sample size in this subgroup which mitigated statistical power. WebNov 6, 2024 · 在13例基线有脑转移的患者中,orr为61.5%,dcr为100%。 3例患者基线有颅内可测量病灶,1例颅内肿瘤达到PR,2例为SD。 此外,伊鲁阿克在克唑替尼耐药的ROS1阳性NSCLC患者中显示出疗效信号,9例克唑替尼耐药的患者中,ORR为22.2%(2例PR),DCR为66.7%,6个月的缓解率为100%,截至数据分析,患者仍在 ... philly to ord
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WebDownload Table Correlation between PFS/TTP, ORR, DCR, and OS from publication: Correlation between overall survival and other endpoints in clinical trials of second-line … WebSep 11, 2024 · The prognoses at least included more than one of the following components: OS, TTP, ORR, DPR, 1-year survival rate and 2-year survival rate. OS referred to the duration from the date of diagnosis to the date of death or lost to follow-up. TTP was defined as the time from randomisation to the appearance of radiologic evidence of disease progression. Web>All secondary efficacy endpoints (PFS, TTP, ORR, CBR, DoR) significantly improved with the addition of trastuzumab (data not shown). >Addition of trastuzumab to chemotherapy was well tolerated, with no difference in the overall safety profile between treatment arms, including cardiac AEs. >Trastuzumab in combination with chemotherapy is a new tsche student verification